刘修营 Staff
刘修营,博士
教育经历
2005年获得华中科技大学大学获得计算机科学与技术专业工学学士学位;
2009年获得东北农业大学动物学专业理学硕士学位,导师白秀娟教授,合作导师王秀杰研究员;
2013年获得中国科学院大学中国科学院遗传与发育生物学研究所生物信息学专业理学博士学位,导师王秀杰研究员。
学习经历
2007.7-2009.9年在中科院遗传发育所王秀杰实验室交流学习,研究方向为生物信息学;
2012.5-2012.12在德州农工大学张绣任实验室进行交流学习,主要从事植物中小分子RNA的研究;
2015.10-2015.12在加州大学圣地亚哥分校张康实验室交流访问,主要从事癌症高通量数据的分析。
工作经历
2013.7-今 中科院遗传发育所 助理研究员
研究兴趣
本人主要是利用已有的算法去分析和挖掘高通量生物数据,包括基因芯片、二代测序、三代测序等数据,从基因组、转录组、蛋白质组、代谢组及宏基因组等多层次多角度地从数据中挖掘和研究疾病的致病机理,更好地服务于社会,服务于人类。
奖励与荣誉
2009-2010 中国科学院研究生院 三好学生
2010-2011中国科学院研究生院 三好学生标兵
2013 中国科学院大学 优秀毕业生
2013 北京市 优秀毕业生
2015 中科院遗传发育所 优秀青年
2016 中科院遗传发育所 优秀工会积极分子
2017 国家公务员心理健康指导员(初级)
代表性论著
1.第一作者论文
(1) Zhonghui Zhang#, Xiuying Liu#, Xinwei Guo, Xiu-Jie Wang*, Xiuren Zhang* Arabidopsis AGO3 predominantly recruits 24-nt small RNAs to regulate epigenetic silencing. Nat Plants. 2016 Apr 18;2(5):16049. (#Co-first author)
(2) Yan Li#, Xiuying Liu#, Li Huang, Huishan Guo*, and Xiu-Jie Wang* Potential coexistence of both bacterial and eukaryotic small RNA biogenesis and functional related protein homologs in Archaea. Journal of Genetics & Genomics 2010 37, 493-503. (#Co-first author)
(3) Xiuying Liu#, Guanzheng Luo, Xiujuan Bai*, and Xiu-Jie Wang* Bioinformatic analysis of microRNA biogenesis and function related proteins in eleven animal genomes. Journal of Genetics & Genomics 2009 36, 591-601.
2.既非第一作者又非通讯作者论文
(1) Mengzhu Chen, Xiuying Liu, Jie Du, Xiu-Jie Wang, Lixin Xia Differentiated regulation of immune-response related genes between LUAD and LUSC subtypes of lung cancers. Oncotarget 2017 8:133-144
(2) Jin-Rui Chang, Jun Guo, Yue Wang, Yue-Long Hou, Wei-Wei Lu, Jin-Sheng Zhang, Yan-Rong Yu, Ming-Jiang Xu, Xiu-Ying Liu, Xiu-Jie Wang, You-Fei Guan, Yi Zhu, Jie Du, Chao-Shu Tang, Yong-Fen Qi Intermedin1-53 Attenuates Vascular Calcification in Rats with Chronic Kidney Disease via Upregulation of Klotho. Kidney International 2016 89, 586–600
(3) Claudia Castillo-González, Xiuying Liu, Changjun Huang, Changjiang Zhao, Zeyang Ma, Tao Hu, Feng Sun, Yijun Zhou, Xiu-Jie Wang, Xueping Zhou, Xiuren Zhang Geminivirus-encoded TrAP suppressor inhibits the histone methyltransferase SUVH4/KYP to counter host defense. 2015 7;4:eLife.06671
(4) Ling Shuai, Yukai Wang, Mingzhu Dong, Xuepeng Wang1, Lisi Sang, Mei Wang, Haifeng Wan, Guanzheng Luo, Tiantian Gu, Yan Yuan, Chunjing Feng, Fei Teng, Wei Li, Xiuying Liu, Tianda Li, Liu Wang, Xiu- Jie Wang, Xiao-Yang Zhao, and Qi Zhou Durable pluripotency and haploidy in epiblast stem cells derived from haploid embryonic stem cells in vitro. Journal of Molecular Cell Biology 2015 7(4).
(5) Xin Liu, Ying Zhang, Man Tong, Xiuying Liu, Guanzheng Luo, Dongfang Xie, Shaofang Ren, Dong-hui Bai, Wang Liu, Qi Zhou, Xiu-Jie Wang Identification of a small molecule 1,4-bis-[4-(3-phenoxy-propoxy)-but-2-ynyl]-piperazine as a novel inhibitor of the transcription factor p53. Acta Pharmacologica Sinica 2013 34, 805-810.
(6) Xinmin Zhang, Yuzhen Ma, Xiuying Liu, Qi Zhou, Xiu-Jie Wang Evolutionary and Functional Analysis of the Key Pluripotency Factor Oct4 and Its Family Proteins. Journal of Genetics and Genomics 2013 40, 399-412.
3.专著
Xianwei Song#, Xiuying Liu#, Xiaofeng Cao*, and Xiu-Jie Wang*. Plant Genetics and Genomics: Crops and Models (Volume 5) Chapter 10: Non-coding regulatory RNAs. Springer. 2013 (#Co-first author)
联系方式
办公电话:010-64806591
手机:13717972094
邮箱:xy.liu@genetics.ac.cn